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Alpha DaRT treatment proves a success in first-in-human trial

Diffusing alpha-emitters radiation therapy (DaRT) uses interstitial radioactive seeds that continually release short-lived alpha-emitting atoms to treat cancer. Researchers in Israel have now published the positive results of a first-in-human clinical study evaluating the feasibility, safety and efficacy of this novel radiotherapy technique (Int. J. Radiat. Oncol. Biol. Phys. 10.1016/j.ijrobp.2019.10.048). The clinical trial examined Alpha DaRT treatment, developed by Alpha Tau Medical. The therapy uses seeds (10 mm long and 0.7 mm diameter) impregnated with Ra atoms, which are implanted percutaneously into a solid tumour. As the Ra decays, short-lived daughter atoms ( Rn, Po, Bi, Po and PB)

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