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Were you diagnosed with Skin Cancer?

Our Clinical Trial Treatment may help you


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Alpha DaRT is a groundbreaking technology that enables for the use of alpha radiation in a localized treatment for skin cancers with a 78% complete response rate* and no harsh side effects.*

Having reveived FDA’s Breakthrough Device Designation for the treatment of SCC of the skin without curative standard of care, the Alpha DaRT is now available in a skin cancer clinical trial led by MSK Cancer Center in NY and other major medical institutions throughout the US.

Alpha DaRT is administered by inserting thin sources emitting alpha radiation directly into the tumor, in a procedure that involves: 

Minimal invasiveness

No costs for enrolled patients

78% complete response*

One time treatment (1-2h)

Local anesthesia

No significant side effects*

*based on previous published study 

The entire treatment process lasts only 2 weeks plus follow-up visits. The seeds are usually removed from the tumor after this period (depending on the judgment of the medical staff).


Participating Doctors

Dr. Noam VanderWalde

Radiation Oncologist

West Cancer Center, Memphis TN

Dr. Mark D'Andrea

Radiation Oncologist


Cancer & Diagnostic Center, Houston TX

Dr. Arshin Sheybani

Radiation Oncologist

UnityPoint Health, Des Moines, IA

Dr. Elie Levy


Dermatology of Seattle & Bellevue, Seattle WA

Relevant types of cancers 

Irrelevant tumor locations

✓   SCC (Squamous Cell Carcinoma)

✓   BCC (Basal Cell Carcinoma)

✓   MCC (Merkel Cell Carcinoma)

✓   Melanoma

✖   Throat

✖   Brain

✖   Tumors located in internal organs   (egsuch as pancreas, stomach, esophagus, cervix, etc)

✖ Oral cavity

Relevant tumor locations

✓   Cheek (external)

✓   Ear

✓   Nose 

✓   Forehead

✓   Skull

✓   Limbs (hands, feet)


✓   Scalp

This clinical trial is designed for the treatment of cancerous tumors; it does not serve a preventive purpose. 

Alpha DaRT Technology 

Alpha particles are known to be very destructive to tumor cells. They cause direct damage to the DNA of malignant cells and destroy them. However, the range of alpha particles in tissue is limited. Therefore, until now, it was not possible to use alpha particles as a treatment for solid tumors.

The Alpha DaRT technology uses the diffusion of atoms that emit alpha particles within the tumor tissue, in order to overcome the limitation of their short range. This makes possible the treatment of entire tumors.

The Alpha DaRT technology is based on small amounts of radioactive radium-224 fixed to metal needles that are inserted into the tumor itself.

When radium-224 decays, it releases radioactive atoms with short lifespans that diffuse inside the tumor. These atoms emit short-range alpha radiation that damages and kills cancer cells within a short period of time. The seeds with radium are placed into the tumor with the help of a piece of thread, which is also used to remove them at the termination of treatment.


Check your suitability


© Alpha Tau Medical Ltd.